Accepting or declining non-invasive ventilation or gastrostomy in amyotrophic lateral sclerosis: patients’ perspectives
نویسندگان
چکیده
منابع مشابه
Predicting the Need for Non-Invasive Ventilation in Patients with Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis (als) is a devastating neurodegenerative disease causing motor impairment. It is the third in the ranking of incidence of neurodegenerative diseases, has no cure, and its survival time after diagnosis is very limited. Since most patients die from respiratory failure, predicting the onset of hypoventilation is of major importance to prolong survival and improve the ...
متن کاملAmyotrophic lateral sclerosis: one or multiple causes?
The Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease in the adulthood, and it is characterized by rapid and progressive compromise of the upper and lower motor neurons. The majority of the cases of ALS are classified as sporadic and, until now, a specific cause for these cases still is unknown. To present the different hypotheses on the etiology of ALS. It was...
متن کاملIs the effect of non-invasive ventilation on survival in amyotrophic lateral sclerosis age-dependent?
BACKGROUND Hypoventilation due to respiratory muscle atrophy is the most common cause of death as a result of amyotrophic lateral sclerosis (ALS). Patients aged over 65 years and presenting bulbar symptoms are likely to have a poorer prognosis. The aim of the study was to assess the possible impact of age and treatment with non-invasive ventilation (NIV) on survival in ALS. Based on evidence fr...
متن کاملThe predictive value of respiratory function tests for non-invasive ventilation in amyotrophic lateral sclerosis
BACKGROUND Non-invasive ventilation (NIV) improves survival and quality of life in amyotrophic lateral sclerosis (ALS) patients. The timing of referral to a home ventilation service (HVS), which is in part based on respiratory function tests, has shown room for improvement. It is currently unknown which respiratory function test predicts an appropriate timing of the initiation of NIV. METHODS...
متن کاملProgranulin mutations and amyotrophic lateral sclerosis or amyotrophic lateral sclerosis-frontotemporal dementia phenotypes.
OBJECTIVE Mutations in the progranulin (PGRN) gene were recently described as the cause of ubiquitin positive frontotemporal dementia (FTD). Clinical and pathological overlap between amyotrophic lateral sclerosis (ALS) and FTD prompted us to screen PGRN in patients with ALS and ALS-FTD. METHODS The PGRN gene was sequenced in 272 cases of sporadic ALS, 40 cases of familial ALS and in 49 patien...
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ژورنال
عنوان ژورنال: Journal of Neurology
سال: 2015
ISSN: 0340-5354,1432-1459
DOI: 10.1007/s00415-015-7665-z